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Item Level of Satisfaction and Associated Factors Among Clients Enrolled In The Community Based Health Insurance Scheme At Asella Referral And Teaching Hospital, Ethiopia(2025-05-01) Wondwosen MulatuAbstract Background: Client satisfaction is a key indicator of healthcare quality and a determinant of the sustainability of Community-Based Health Insurance (CBHI) schemes. Evidence on satisfaction levels and associated factors remains limited in Ethiopia, particularly in referral hospital settings. Objective: To assess the level of client satisfaction and identify associated factors among CBHI-enrolled clients at Asella Referral and Teaching Hospital (ARTH), Arsi Zone, Ethiopia. Methods: An institution-based cross-sectional study was conducted from August 11 to November 30, 2025, among 402 CBHI-enrolled clients. Data were collected using a structured interviewer-administered questionnaire, with satisfaction measured on a 5-point Likert scale. Binary and multivariable logistic regression analyses were performed. Variables with p < 0.20 in bivariate analysis were included in the multivariable model, and statistical significance was set at p < 0.05. Results: The overall client satisfaction level was 75.9% (mean score = 3.84 ± 0.59). Most respondents intended to renew CBHI membership (99.3%) and reported high satisfaction with staff courtesy and hospital cleanliness (> 95%). However, major service gaps were identified: 69.2% of clients did not receive all prescribed medications, and 71.4% did not obtain all requested laboratory services, resulting in the lowest satisfaction score for out-of-pocket payments (mean = 2.90 ± 1.32). Clients aged 18 – 29 years (AOR = 0.33; 95% CI: 0.12 – 0.90) and 30 – 44 years (AOR = 0.38; 95% CI: 0.15 – 0.95) were less likely to be satisfied compared to those aged ≥ 60 years. Lower educational status, longer CBHI enrollment (≥5 years), and participation in CBHI meetings (AOR = 1.70; 95% CI: 1.00 – 2.91) were associated with higher satisfaction. Conclusion: Although overall satisfaction and intention to renew CBHI membership were high, significant dissatisfaction related to the availability of essential drugs and diagnostic services persisted. Client satisfaction was influenced by age, education level, duration of enrollment, and scheme engagement. Improving the availability of medicines and laboratory services, strengthening communication, and addressing the expectations of younger and more educated clients may enhance satisfaction and support the sustainability of the CBHI program. Keywords: community based health insurance, client satisfaction, associated factors, hospital services, ethiopian cbhi schemeItem MAGNITUDE OF POST-TUBERCULOSIS LUNG DISEASES AND ASSOCIATED FACTORS AMONG ADULT PATIENTS ADMITTED TO ASELLA REFERRAL AND TEACHING HOSPITAL, ETHIOPIA(2025-05-01) MISHA BONKA SHAMANAAbstract Introduction: Globally an estimated 155 million tuberculosis (TB) survivors were alive in 2020, of whom approximately 27 million people could be identified and evaluated for ‘post-tuberculosis lung disease’ (PTLD). The post-TB lung disease is a chronic respiratory disease that persists even after successful completion of treatment for primary tuberculosis. Its global prevalence may reaches up to 59% among patients with history of TB treatment. However, data on its prevalence and associated factors is lacking in Ethiopia. Methodology: An institution based cross-sectional study was conducted on patients who had a history of pulmonary tuberculosis treatment and were admitted to the medical ward over six years, from January 1, 2019, to December 31, 2024, to assess the magnitude and associated factors of post-tuberculosis lung disease. A total of 181 participants were selected by simple random sampling. Data were collected from logbooks and patient charts using checklists on koboToolbox and analyzed using SPSS version 31. Descriptive statistics were carried out, and categorical variables were reported as frequencies and percentages, whereas mean and median reporting was used for numerical variables. Crude odds ratios with their 95% confidence intervals (CI) were estimated in the bivariate logistic regression and those variables with a P value < 0.25 in the bivariate logistic regression were fitted into the multivariable logistic regression analysis. The strength of association was reported using adjusted odds ratios with 95% CI, and P value < 0.05 was declared as statistically significant. Results: Among the 181 studied individuals, one-third (33.7%) had bacteriologically confirmed pulmonary tuberculosis. The overall prevalence of PTLD was 65.19% (95% CI: 58.25-72.13%). Age older than 60 years (AOR = 20.22, 95% CI: 3.64-112.21, p = <0.001), rural residence (AOR = 7.05, 95% CI: 1.8-27.1, p = 0.005), cigarette smoking (AOR = 182.98, 95% CI: 4.11-813.08, p = 0.007), history of PTB recurrence (AOR = 8.27; 95% CI: 1.40-48.68, p = 0.020), and poor compliance with previous PTB treatment (AOR = 8.62; 95% CI: 1.66-44.80, p = 0.010) were independently associated with developing PTLD. However, HIV seropositivity was associated with reduced risk of PTLD (AOR = 0.073, 95% CI: 0.017-0.310, p < 0.001). Conclusion: This study revealed that PTLD is 65.19% among admitted patients and significantly associated with age 60 years or older, recurrent tuberculosis, poor adherence to prior tuberculosis treatment, cigarette smoking, and rural residence. Keywords: Post-tuberculosis lung disease, PTLD prevalence, Asela Referral and Teaching Hospital, Ethiopia.Item ASSESSMENT OF ANTIBIOTICS PRESCRIPTION PATTERN AND ASSOCIATED FACTORS AMONG PATIENTS ADMITTED TO MEDICAL WARD OF ASELLA REFERRAL AND TEACHING HOSPITAL SOUTHEAST, ETHIOPIA(2025-05-01) NAHOM PAULOSABSTRACTS Background: Antibiotics are vital for treating bacterial infections and reducing morbidity and mortality worldwide. However, widespread misuse and inappropriate prescribing have led to significant antibiotic resistance. In response, the WHO and national health authorities promote antimicrobial stewardship to optimize antibiotic use. Generating local evidence on prescribing practices is crucial for developing context-specific stewardship interventions. This study assessed antibiotic prescribing patterns and associated factors among patients admitted to the medical ward of Asella Referral and Teaching Hospital, Southeast Ethiopia. Objective: To assess antibiotics prescription pattern and identify factors associated with inappropriate antibiotic use among patients admitted to medical ward of Assela Referral and Teaching Hospital Methodology; An institution-based retrospective cross-sectional study was conducted at Assela Referral and Teaching Hospital medical ward. A total of 228 patient charts were reviewed in the study period. Data analysis was done using SPSS version 27. Descriptive statistics were performed to show the prevalence and frequencies of the collected variables. Those variables that show associations with the dependent variable at p <0.25 in the bi-variate analysis were entered into the multiple logistic regression. Adjusted odds ratios with their corresponding 95% confidence intervals and p-values were used to assess the strength of the associations. Variables with p-values of less than 0.05 in the multiple regressions were finally considered as statistically significant. Result: Of the 228 patient records reviewed, 50.9% were male, and 54.8% were aged 31–64 years. Community acquired pneumonia was the most common diagnosis (20.6%). Ceftriaxone was the most frequently prescribed antibiotic (22.8%) of all prescriptions. Overall, 33% of participants received inappropriate prescriptions. In multivariable logistic regression, patients who do not have culture result show significant rate of inappropriate prescription pattern (AOR = 8.79; 95% CI: 1.98–39.05). Receiving two or more antibiotics was independently associated with higher odds of inappropriate prescription (AOR = 2.42; 95% CI: 1.15–5.10) and patients whose antibiotics was not de-escalated were associated with inappropriate antibiotics use (AOR = 2.40; 95% CI: 1.01–5.70). Conclusion: One third of antibiotic prescriptions for medical inpatients were inappropriate. Culture result, Receiving two or more antibiotics and antibiotics de-escalation were independently associated with higher odds of inappropriate prescription. These findings highlight the need for routine antimicrobial stewardship interventions, prescriber education, and evidence based antibiotics treatment. Key words: antibiotic prescribing pattern; inappropriate antibiotic use; medical ward; WHO prescribing indicators; EthiopiaItem PREVALENCE OF ACUTE KIDNEY INJURY AND ASSOCIATED FACTORS AMONG ACUTE HEART FAILURE PATIENTS ADMITTED AT ASELA REFERRAL AND TEACHING HOSPITAL, ARSI UNIVERSITY, ASELLA, CENTRAL ETHIOPIA(2025-05-01) MELAKU ABDUREHMANABSTRACT Introduction: Heart failure often leads to hospitalization and can directly impact other organs, such as the kidneys. Acute kidney injury (AKI) is a common complication in patients hospitalized for acute decompensated heart failure (ADHF) and is associated with worse outcomes. However, there are limited data on the magnitude of AKI among hospitalized ADHF patients in resource-limited settings such as Ethiopia. Objective: To assess the prevalence of acute kidney injury and associated factors among acute heart failure patients admitted at Asela Teaching and Referral Hospital, central Ethiopia, from May to December 2025. Methodology: An institution-based cross-sectional study was conducted to determine the prevalence of acute kidney injury and associated risk factors among acute heart failure patients at Asela Teaching and Referral Hospital. A total of 180 admitted patients were included. Data were collected using structured questionnaires and analyzed using EPI Info and SPSS version 27. Descriptive statistics were summarized using frequencies, percentages, and medians. Bi-variate logistic regression was performed to identify candidate variables (p < 0.2), which were entered into multivariable logistic regression. Associations were reported using adjusted odds ratios with 95% confidence intervals, and p < 0.05 was considered statistically significant. Results: A total of 121 patients admitted with acute decompensated heart failure were included in the study. Acute kidney injury occurred in 29 patients, giving a prevalence of 24% (95%CI17.2-32.3%. In multivariable logistic regression analysis, diabetes mellitus (AOR=67.74; 95%CI: 6.53-702.34; p<0.001), presence of infection (AOR=27.78; 95%CI: 3.40-227.28; p=0.002) , and atrial fibrillation (AOR=17.75;95%CI 3.09-101.81;p=0.001) were independently associated with the development of AKI. Conclusion: Acute kidney injury was a common complication among patients admitted with acute decompensated heart failure. Diabetes mellitus, infection, and atrial fibrillation were identified as independent predictors of AKI. Keys- acute decompensated heart failure, acute kidney injuryItem BARRIERS TO EFFECTIVE INSULIN THERAPY IN ADULT PATIENTS WITH POORLY CONTROLLED TYPE 1 DIABETES MELLITUS: A STUDY AT ASELLA REFERRAL AND TEACHING HOSPITAL, ARSI UNIVERSITY, ETHIOPIA (2025).(2025-05-01) GEMECHU MERIBOAbstract Background: Poor glycemic control remains a major challenge in the management of diabetes mellitus and is associated with increased morbidity and mortality. This study aimed to assess the barriers to effective insulin therapy in adult patients with poorly controlled type 1 diabetes mellitus attending Asella Referral and Teaching Hospital, Ethiopia. Objective: To assess the barriers that hinder effective insulin therapy in adult patients with poorly controlled T1DM attending the diabetic follow-up clinic at Asella Referral and Teaching Hospital, Asella, Ethiopia in 2025. Methodology: A cross-sectional study was conducted among 273 type 1 adult diabetes patients on follow-up at ARTH. Data was collected by kobotool box and was entered using and analyzed by SPSS version 27. Descriptive statistics was carried out, and categorical variables were reported as frequencies and percentages whereas; median and interquartile range (IQR) was used for continuous variables. Binary logistic regression analysis was applied to identify barriers associated with poor glycemic control in adult patients with type 1 DM. P value < 0.25 in the bivariate logistic regression was fitted into the multivariable logistic regression analysis. The level of significance was declared at a p-value of <0.05. Results: Out of 273 type 1 diabetes patients included in the study, 157 (57.5%) had poor glycemic control.The factors associated with poor glycemic control were depression (AOR = 2.92; 95% CI: 1.39–5.95.15; p = 0.004), lower monthly income (AOR=1.54;95% CI[1.30-2.96];p=0.049),basal-only insulin regimens (AOR = 2.045;95%,CI :1.055-3.964; p = 0.034), and good adherence (AOR = 0.39; 95% CI: [0.16–0.97]; p=0.04). Conclusion:The occurrence of poor glycemic control is high among adult patients with diabetes who visit ARTH.The results emphasize the view that ideal glycemic control must be an integrated methodology that covers mental health, socioeconomic issues, and compliance with therapy, in addition to clinical management Key words: Type 1 diabetes mellitus, Glycemic control, ARTH, EthiopiaItem PREVALENCE AND DETERMINANT FACTORS OF CARDIOVASCULAR AUTONOMIC NEUROPATHY AMONG ADULT PATIENTS WITH DIABETES MELLITUS AT ASELLA REFERRAL & TEACHING HOSPITAL, ETHIOPIA(2025-05-01) GADISA TADESEABSTRACT Background: Diabetic cardiovascular autonomic neuropathy (CAN) is a serious but often missed diabetes complication, damaging nerves that control heart and blood vessel functions. In Ethiopia, data on CAN is limited, screening protocols are lacking, and awareness is low, calling for research to improve diabetes care. Objective: To assess the prevalence of cardiovascular autonomic neuropathy and identify determinant factors among adult patients with diabetes mellitus attending follow-up at the diabetic clinic of Asella Referral and Teaching Hospital, Asella, Ethiopia. Method: An Institution-based cross-sectional study was conducted at Asella Referral & Teaching Hospital from July 1 to December 30, 2025. A systematic random sampling technique was employed to select 392 participants. Data were collected by trained data collectors using pretested, structured, interviewer-adminstred questioners and standardised tests (CARTs). The collected data was exported to SPSS version 27.0 for comprehensive statistical analysis. A bivariate and multivariable logistic regression was applied to asses associations between dependent and independent variables. The odds ratio with a 95% CI was used to declare the strength of associations between dependent and independent variables. p-values less than 0.05 were considered statistically significant. Results were summarized and presented through texts, tables, and figures. Result: Among 392 diabetic patients, CAN was prevalent in 66.1% (n = 259), with 35.0% exhibiting early CAN, 25.3% definite CAN and 6.1 severe CAN according to Ewing’s severity score. Multivariable logistic regression identified female sex (AOR = 1.773, 95%CI: 1.008-3.117, p-value = 0.047), unemployment (AOR = 2.237, 95%CI: 1.026-4.876, p-value = 0.043), longer diabetes duration (≥10 years; AOR = 6.562, 95% CI: 3.38–12.739, p-value < 0.001), poor glycaemic control (3 month average FBS >130; AOR = 4.452, 95% CI: 2.548–7.779, p-value < 0.001), and hypertension (AOR = 2.817, 95% CI: 1.332–5.957, p-value = 0.007) as independent risk factors for CAN. Conclusion and Recommendation: These findings highlight the substantial burden of CAN in this population and the critical role of modifiable risk factors. Routine screening for CAN using standardized autonomic testing should be incorporated into diabetes care, particularly for patients with prolonged disease duration, suboptimal glycaemic control, or hypertension. Keywords;CARTs, Ewing’s battery tests, cardiovascular autonomic neuropathyItem Characteristics and prognostic outcomes of central nervous system tuberculosis among adults at Asella referral and teaching hospital(2025-05-01) Dinka fikaduABSTRACT Background Central nervous system (CNS) tuberculosis (TB) is among the relatively uncommon yet most devastating forms of human mycobacterial infection. The estimated mortality of CNS-TB is approximately 42% in hospitalized patients (based on meningitis related deaths). However, hospital outcomes of CNS-TB and its predictors are not well studied in the study area. Objectives To Asses Clinical Characteristics, treatment outcomes and its associated factors of central nervous system tuberculosis among adults at Asella referral and teaching hospital. Methodology: Institutional based Cross-sectional study was conducted on CNS TB Patients who presented to Asella referral and teaching hospital during the study period. Data were collected from the patient’s’ medical records using a checklist created on kobo toolbox. A total sample size of 130 was included and analyzed using Statistical Package for Social Science (SPSS) version 27. Bivariate and multivariate logistic regression analysis was applied to assess associations between dependent and independent variables. The odds ratio with a 95% confidence interval was used to declare the strength of associations between dependent and independent variables. P values less than 0.05 was considered statistically significant. Results: A total of 130 participants were included in the study. Among them, 74 (56.9%) were male. The mean age of participants was 43.22 ± 14.98 years. The clinical presentation of CNS TB revealed that headache, fever, and neck rigidity were reported by 125 participants (96.15%). Regarding treatment, only 4 participants (3.08%) did not receive TB treatment, while 126 (96.92%) did. The initiation of drug therapy occurred in less than two weeks for 60 participants (46.2%). At discharge, 111 participants (85.38%) showed improvement, although there were 11 deaths (8.46%), and 3 referrals (2.31%). In the multivariable logistic regression models, age, duration of drug initiation, and HIV status were statistically significant predictors of poor treatment outcomes for CNS TB. Age emerged as a critical risk factor, especially for those over 65 years, who faced a significantly increased risk of poor treatment outcomes (AOR 3.23, 95% CI 2.62-7.21, p < 0.001). Patients whose treatments initiated after more than two weeks had poor treatment outcomes (AOR 4.56, p < 0.001), and those with reactive HIV tests faced a higher risk of poor treatment outcomes (AOR 2.66, p = 0.002). Conclusion: A significant majority of the participants were male, with an average age of around 43 years. Notably, classic symptoms such as headache, fever, and neck rigidity were predominant among patients, with severe neurological complications like seizures and cognitive impairments documented. The diagnosis of TB meningitis was the most common. However, a concerning 8.46% of cases resulted in death. Age, timing of drug initiation, and HIV status as significant predictors of poor treatment outcomes. Particularly alarming was the increased risk in patients over 65 years and those who delayed treatment. Key words: clinical characteristics, Central Nerve system TB and treatment outcomeItem Assessment of clinical profile, treatment outcome, and associated factors among aluminum phosphide poisoning patients at Asella referral and teaching hospital, Arsi university(2025-05-01) Fitsum MolaABSTRACT Background: Aluminum phosphide (AlP) is an economical, widely utilized rodenticide and solid fumigant associated with an exceptionally high case fatality rate. In Ethiopia, AlP poisoning has emerged as a significant public health issue, marked by elevated mortality and a lack of extensive local research. Because no specific antidote exists, identifying clinical predictors is essential for improving survival through optimized supportive care. Objective: To assess the clinical profile, treatment outcomes, and associated factors among aluminum phosphide poisoning patients presented to the adult emergency department of Asella Referral and Teaching Hospital (ARTH), central Ethiopia. Methods: An institution-based cross-sectional study was conducted analyzing 116 eligible cases presented between August 2020 and 2025. All eligible AlP poisoning cases were included to maximize statistical power. Data were extracted from medical registries using a structured tool and analyzed via SPSS version 26. Descriptive statistics will be conducted to characterize the study population. Bivariate and multivariable logistic regression models were employed to identify independent predictors of mortality, with statistical significance set at p < 0.05. Results: Among the 116 cases, the majority were female (58.8%), rural residents (79.3%), and young adults with a mean age of 26 years. All instances (100%) were identified as intentional self-harm. The most common clinical manifestations were vomiting (100%), epigastric pain (93%), and initial hypotension (40.5%). Despite medical management, including the use of magnesium sulfate and calcium gluconate in nearly half of the cases, the overall mortality rate was 31%. Multivariable analysis identified two independent predictors of the mortality: initial hypotension (SBP ≤ 90 mmHg) (AOR = 264.946; 95% CI: 1.175, 5.9x10⁴, p = 0.044), and a hospital stay of less than two days (AOR = 167.269; 95% CI: 4.282, 6534.394, p = 0.006). Conclusion: Aluminum phosphide poisoning remains a highly lethal method of self-harm. Hemodynamic instability and a hospital stay of less than two days—serve as the primary determinant of mortality. These findings underscore the need for rapid hemodynamic support. Keywords: Aluminum phosphide, Clinical profile, Mortality, Associated factors, EthiopiaItem MAGNITUDE OF POST-STROKE DEPRESSION AND ASSOCIATED FACTORS AMONG STROKE SURVIVORS ON FOLLOW-UP AT NEUROLOGY AND MEDICAL REFERRAL CLINICS AT ASELLA REFERRAL AND TEACHING HOSPITAL, ARSI UNIVERSITY, ASELLA, ETHIOPIA(2025-05-01) Denebo BulbulaAbstract Background: Post-stroke depression is among the most common neuropsychiatric complications in stroke survivors, affecting approximately one-third of stroke survivors at any point in time after stroke. Clinicians often under-recognize and under-treat post-stroke depression. Studies on post-stroke depression have been done in various countries. However, there are limited studies done in the Oromia region, and no studies have been done in the study area in particular. Objective: To assess the magnitude of post-stroke depression and associated factors among stroke survivors on follow-up at neurology and medical referral clinics at ARTH from June 1, 2025, to December 31, 2025. Methods: An institution-based cross-sectional study was conducted based on a structured questionnaire, patient interviews, and a review of patient charts All the necessary data were collected from patients on follow-up at neurology and medical referral clinics using the pre-developed data collection format by Kobo Toolbox. A systematic random sampling method was used to identify the participants’ charts. After data collection was completed, data on kobo Toolbox were downloaded as Excel and exported to the SPSS 27 version software database for analysis. Bivariate logistic regression analysis was used to identify the candidate variables at p value <0.25, and multivariable logistic regression analysis was employed to identify significant factors at p value <0.05 Results: A total of 148 stroke survivors participated in the study, with a response rate of 97.4%. The overall prevalence of post-stroke depression was 33.1%(95% CI:25.5%- 40.7%). It was significantly associated with the degree of disability, marital status, occupation, and diabetes mellitus. Conclusion: The study showed that one-third of stroke survivors in our study area had post-stroke depression. It had a strong association with the degree of disability, marital status, occupation, and diabetes mellitus, with the degree of disability showing the strongest and most independent association with post-stroke depression. Routine screening and early management of depression should be integrated into post-stroke follow-up care. Keywords: Stroke, post-stroke depression, Prevalence, Associated factors, Neurology Clinic, AsellaItem KNOWLEDGE TOWARDS STROKE AND DETERMINANT FACTORS AMONG PATIENTS WITH HYPERTENSION AND DIABETIES ATTENDING CHRONIC FOLLOW UP CLINIC AT ASELLA REFERRAL AND TEACHING HOSPITAL (ARTH)(2025-05-01) DENEBO JEBESOAbstract Background: Stroke is a leading cause of death and disability worldwide, with an increasing burden in sub-Saharan Africa. Hypertension and diabetes mellitus are the primary modifiable risk factors for stroke. Adequate knowledge of these risk factors, warning signs, and appropriate responses is essential for prevention and early treatment; however, data on high-risk patients in southeastern Ethiopia is scarce. Objective: To assess knowledge of stroke and its determinants among patients with hypertension and/or diabetes attending the chronic follow-up clinic at Asella Referral and Teaching Hospital. Methods: A cross-sectional study was conducted from May 2025 to January 2026 at Asella Referral and Teaching Hospital. A total of 407 adult patients with hypertension and/or diabetes were selected using convenience sampling. Data were collected through a structured interviewer-administered questionnaire and analyzed using SPSS version 27. Bivariate and multivariable logistic regression analyses identified factors associated with stroke knowledge, with a p-value <0.05 considered statistically significant. Results: Among the study participants, 76.9% (95% CI: 73.0–81.3) had good overall knowledge of stroke, while 23.1% had poor knowledge. Good knowledge of stroke risk factors was observed in 88.9% (95% CI: 85.7–91.9) of participants, and 88.5% demonstrated good knowledge of stroke signs and symptoms. Regarding planned response to stroke, 62.4% reported that they would seek medical care immediately. Factors significantly associated with good stroke knowledge included urban residence (AOR = 2.25; 95% CI: 1.19–4.25), higher educational status, higher monthly income, and good knowledge of stroke risk factors (AOR = 5.85; 95% CI: 2.81–12.17). Conclusion: While most patients with hypertension and/or diabetes exhibited good knowledge of stroke, significant gaps exist among rural residents and those with lower educational attainment. Enhancing targeted health education during follow-up visits is crucial for improving stroke prevention and timely healthcare seeking. Keywords: Stroke, Hypertension, Diabetes Mellitus, Knowledge, EthiopiaItem THE EVOLVING BURDEN OF LIVER DISEASE IN THE ART ERA: MAGNITUDE AND DETERMINANTS AMONG HIV SERO-POSITIVE PATIENTS AT ASELLA REFERRAL AND TEACHING HOSPITAL, ETHIOPIA, 2026(2025-05-01) YOHANES ZEBENUABSTRACT Background: Liver disease remains a significant cause of morbidity and mortality among people living with human immunodeficiency virus, even in the era of widespread antiretroviral therapy. Multiple factors, including demography, clinical status, and treatment related effects, may contribute to liver disease in this population. However, data from resource limited settings like Ethiopia remains limited. Objective; To determine the magnitude of liver disease and associated factors among human immunodeficiency virus sero-positive patients on follow up at Asella referral and teaching hospital, Arsi Zone, Ethiopia. Methods: An institution-based cross-sectional study was conducted from October to December, 2025. Data on socio-demographic, behavioral, and clinical characteristics were gathered using a structured questionnaire and a thorough review of medical records. Liver disease was defined based on biochemical criteria. Data were entered and analyzed using SPSS version 27. Variables with a P-value < 0.25 in the bivariate analysis were entered into the multivariate model, and statistical significance was declared at a p-value < 0.05. Results: A total of 288 participants were included in the final analysis, with a mean age of 45.6 years. Females represented 61.1% (n=176) of the cohort. The overall prevalence of liver disease was 27.4% (95% CI: 0.222 – 0.326). In multivariable logistic regression analysis, male sex was significantly associated with higher odds of liver disease (AOR = 2.698; 95% CI: 1.340 - 5.431). Participants with a history of tuberculosis had nearly four-fold increased odds of liver disease (AOR = 3.944; 95% CI: 2.044 - 7.611), while under nutrition was the strongest predictor of hepatic injury (AOR = 4.996; 95% CI: 2.373 - 10.518). Other factors, including age, viral load, CD4 count, and ART regimen, were not significantly associated with liver disease. Conclusion: This study identified a high prevalence of liver disease (27.4%) among adults living with HIV in Asella. Male sex, under nutrition, and a history of tuberculosis were identified as the key determinants of hepatic complications. These findings suggest that liver health monitoring and nutritional support should be prioritized for these specific high-risk subgroups to improve long-term clinical outcomes. Key Words; Liver disease, HIV patients, Hepatotoxicity, ART, Viral hepatitis, EthiopiaItem Intention To Use Vasectomy and Its Predictors Among Married Men Attending Reproductive Health Services at Public Health Facilities of Asella Town, Arsi Zone, Oromia, 2025(2025-05-01) Natnael LegesseAbstract Background: Vasectomy is a safe, simple, and highly effective method of permanent male contraception. Despite its benefits such as cost-effectiveness, minimal invasive nature, brief procedure duration (10 – 20 minutes), and fewer complications than female sterilization, it is still notably underused in low- and middle-income nations, including Ethiopia. Considering the inconsistencies present in the literature and clear knowledge gaps, it is essential to investigate the factors that affect men's intention to consider vasectomy to develop effective reproductive health strategies and encourage male participation in family planning. Objective: To assess intention to use vasectomy and its predictors among married men attending reproductive health services at public health facilities of Asella Town, Oromia Method: An institution based cross-sectional study design was employed to collect data from 267 married men attending at selected public health facilities of Asella Town. By using a simple random sampling technique, participants were selected, and data was collected using a structured questionnaire. It was entered into EPI data version 4.6 and then exported to Statistical Package for the Social Sciences version 25 for analysis. Bivariate regression analysis was done, and all variables with a p-value < 0.25 in the bivariate analysis was entered into the multivariable analysis. Finally, significance was set at a P-value < 0.05. The study achieved a 97.4% response rate, ensuring sampling adequacy. Result: The magnitude of intention to use vasectomy among married men in this study was 24.2% (95% CI: 19.6–29.6). Factors significantly associated with intention to use vasectomy included urban residency (AOR = 2.56, 95% CI: 1.08–6.10), being employed as a daily laborer (AOR = 5.12, 95% CI: 1.01–25.94), and having good knowledge of vasectomy (AOR = 2.27, 95% CI: 0.98–5.25). Although the confidence interval for knowledge included 1.0, the variable approached statistical significance and warrants further exploration. Conclusion and Recommendation: This study highlights a low intention to use vasectomy and identify key socio-demographic and knowledge-related factors influencing men’s willingness. Public health interventions should focus on improving men’s knowledge of Vasectomy, addressing misconceptions, promoting positive Attitudes, and targeting rural communities. Health education and counseling programs involving both men and couples are critical to enhance vasectomy acceptance. Further research is recommended to explore cultural, behavioral, and health system barriers to male sterilization in Ethiopia.Item CLINICAL PROFILE, SHORT-TERM OUTCOMES AND ASSOICITED FACTORS OF NON-SURGICALLY MANAGED CONGENITAL HEART DISEASES IN PEDIATRICS PATIENTS AT ASELLA TEACHING AND REFERRAL HOSPITAL, ETHIOPIA(2025-05-01) Kasim BenkaAbstract Background: Congenital heart disease (CHD) is a leading cause of morbidity in children, particularly in low-resource settings where surgical intervention is limited. Understanding the clinical profile and short-term outcomes of non-surgically managed CHD is essential to guide care. Methods: A retrospective cohort study was conducted at Asella Teaching and Referral Hospital, Ethiopia, from March 2020 to February 2025 among 156 pediatric patients with CHD. Data on demographs, clinical presentation, CHD types, comorbidities, anthropometric status, hospital admissions, medical management, and six-month clinical outcomes , further reclassified poor outcome(Death and / or DAMA) and good outcome (improved discharged and / or referred after stabilization) were collected from medical records. Descriptive statistics summarized the findings, and multivariable logistic regression identified factors associated with poor outcomes. Results: The majority of patients were infants (<1 year, 46.8%) and from rural areas (69.2%), with slight male predominance (54.5%). Most were symptomatic (91.7%), presenting with fast breathing (75.2%) and feeding difficulties (55.9%). Acyanotic CHD predominated (82.1%), with ventricular septal defect most common (41.7%); cyanotic CHD accounted for 17.9%, predominantly Tetralogy of Fallot (15.4%). Moderate or severe malnutrition affected 50% of patients. Hospital admission occurred in 82.7%, mainly for heart failure (79.8%) and pneumonia (53.5%). Medical management, primarily furosemide (73%) and spironolactone (69.5%), was provided in 76.9% of cases. At six months, 76.9% had good outcomes, while 23.1% had poor outcomes. Down syndrome (AOR = 4.63, 95% CI: 1.15–18.61, p = 0.031, short (≤3 days) (AOR = 6.01, 95% CI: 1.02–35.54, p =0.049) or prolonged (>14 days) hospital stay (AOR = 7.41, 95% CI: 1.08–50.93, p = 0.042), and loss to follow-up (AOR = 0.13, 95% CI: 0.04–0.41, p = 0.001)were independent predictors of poor outcomes. Conclusion: Pediatric CHD patients managed non-surgically are mostly infants with high rates of malnutrition. Continuous follow-up, nutritional support, and attention to comorbidities such as Down syndrome are essential to improve survival and functional outcomes.Item Health care workers cervical cancer screening service provision and associated factors in public health facilities in Asella Town, Oromia, Ethiopia, 2025 G.C(2025-05-01) Tilahun SahluAbstract Background: Cervical cancer, ranking as the fourth most common cancer and also the fourth leading cause of cancer death among women worldwide, claimed an estimated 662,000 new cases and around 349,000 death in 2024. The burden is disproportionately high among the developing countries, majorly Sub-Saharan Africa where limited access to Human papilloma (HPV) vaccines, Organized screening, and timely treatment. Despite the high burden, evidence regarding cervical cancer screening practices in the study area remains limited. Objective: To assess cervical cancer screening service provision and associated factors among health care professional in public health facilities in Asella town, Oromia, Ethiopia,2025. Methods: An institution-based cross-sectional study was conducted at Asella Referral and Teaching Hospital (ARTH) and two public health centers in Asella town, located in the Arsi Zone of the Oromia Region, Ethiopia. The study was conducted from August 1, 2025 to October 30, 2025 on sample size of 181. A simple random sampling technique was employed to select participants proportionally from each health facility. Data were collected using Kobo toolbox V3.3, after data checked for completeness, exported to Statistical Package for the Social Sciences version 28 for analysis. Frequency, mean and standard deviation were used as descriptive statistics. Both binary and multiple logistic regression was conducted. Adjusted odds ratios (AOR) with 95% confidence intervals (CI) were reported to measure the strength of associations. At p-value of less than 0.05 was considered statistically significant. Results were presented using tables, charts. Result: According to this study 63(34.8%) with (95% CI: 27.9,41.4) of study participants reported as they ever did visual inspection under acetic acid or ligol’s iodine for their clients. Level of education having degree, (AOR = 7.3, 95% CI: 2.1,25.15), Level of knowledge with (AOR = 0.303, 95% CI: 0.123,0.74) and received training on VIA with (AOR = 5.27, 95% CI:1.73,16.1) were associated factors to practice cervical cancer screening in the study area. Conclusion: This study revealed a low level of VIA/VILI practice among healthcare providers when compared to WHO standards. These findings indicate that limited training, inadequate knowledge, and lower professional qualification are major barriers to the implementation of cervical cancer screening services in the study area. Keywords: Knowledge, Attitude, Practice, Cervical Cancer Screening, Health Care Workers, EthiopiaItem Determinants of delay in timely treatment seeking for diarrheal diseases among mothers with under-five children in public health facilities of Asella town, Oromia, central Ethiopia: a case - control study(2025-05-01) Abdisa GonfaAbstract Background: Early treatment of diarrheal disease reduces morbidity and mortality among under-five children. However, in many low-income countries, mothers and caregivers often fail to seek care promptly or do not seek care at all. Delayed treatment may result in chronic diarrhea, malabsorption, malnutrition, growth retardation, and long-term impairment. Factors such as maternal knowledge, type of diarrhea, and distance to health facilities influence treatment-seeking behavior. This study aimed to identify determinants of delayed treatment seeking for diarrheal disease among under-five children attending public and private health facilities in Asella town, Oromia region, central Ethiopia. Methods: An institutional-based unmatched case–control study was conducted from October 1 to November 30, 2025, among 324 under-five children (162 cases and 162 controls). Three government and two private health facilities were selected, and the sample size was proportionally allocated to each facility. Data were collected using a pretested questionnaire and analyzed using SPSS version 27. Variables with a p-value ≤0.25 in bivariate analysis were entered into multivariable logistic regression. Statistical significance was declared at p-value <0.05 with 95% confidence intervals. Results: A total 324 participants were included, giving a 100% response rate. Children under 24 months were more likely to experience delayed treatment seeking than those aged ≥24 months (AOR = 2.19; 95% CI: 1.23–3.99). Living more than 10 km from the nearest health facility increased the likelihood of delayed treatment (AOR = 2.67; 95% CI: 1.67–4.27). Children of mothers or caregivers with poor knowledge were also more likely to delay seeking treatment (AOR = 2.60; 95% CI: 1.50–4.43). Conclusion and recommendation: Delayed treatment seeking was significantly associated with younger child age, long distance to health facilities, and poor mothers/caregivers knowledge. Strengthening community-based health education and improving access to health services are essential. Targeted interventions for high-risk families are necessary to reduce diarrhea-related morbidity and mortality among under-five children. Keywords: Diarrhea, Ethiopia, treatment delay, under-fiveItem MATERNAL SATISFACTION WITH CESAREAN SECTION PAIN MANAGEMENT AND ITS ASSOCIATED FACTORS AT ASELLA REFERRAL AND TEACHING HOSPITAL, ETHIOPIA, 2026(2025-05-01) WORKENAH KASSAYEABSTRACT Background: Cesarean section is a common obstetric procedure that reduces maternal and neonatal morbidity and mortality when indicated. However, postoperative pain remains a major challenge, particularly in low and middle-income countries, and may negatively affect recovery and maternal satisfaction. Maternal satisfaction with postoperative pain management is an important indicator of obstetric care quality, yet evidence on its determinants is limited in Ethiopia. Objective; This study aimed at assessing maternal satisfaction with postoperative pain management following cesarean section and factor associated with it. Methods: Facility based cross-sectional study was conducted from July1,2025 to November 30,2025 among women who underwent cesarean section at Asella referral and teaching hospital in Ethiopia. A total of 309 participants were selected using systematic random sampling. Data were collected using a structured, pretested, interviewer-administered questionnaire. Postoperative pain was assessed using a standardized pain scale, and maternal satisfaction was measured using validated tools. Data were analyzed using descriptive statistics and multivariable logistic regression, with statistical significance set at p < 0.05. Results: A total of 309 participants were enrolled in the study. Overall, 54.5% of women reported being satisfied with postoperative pain management. Factors independently associated with satisfaction included prior surgical experience (AOR = 2.33; 95% CI: 1.27–4.26; p = 0.006), receipt of adequate preoperative information (AOR = 2.48; 95% CI: 1.35–4.56; p = 0.004), alleviation of preoperative anxiety (AOR = 2.60; 95% CI: 1.49–4.53; p = 0.001), use of a nerve block (AOR = 12.20; 95% CI: 2.52–59.09; p = 0.002), midline incision (AOR = 3.36; 95% CI: 1.37–8.20; p = 0.008), regular healthcare worker visits (AOR = 2.49; 95% CI: 1.10–5.65; p = 0.028), and provision of information about pain relief options (AOR = 1.91; 95% CI: 1.11–3.29; p = 0.020). Conclusion and Recommendations: Improving satisfaction requires a patient-centered, multidimensional approach beyond pain reduction alone. Strengthening preoperative counseling, optimizing multimodal analgesia, enhancing provider–patient communication, and standardizing pain management protocols are essential to improving maternal experience and quality of obstetric care. Hospitals should institutionalize structured postoperative visits and prioritize patient centered care. Keywords: Cesarean section; Postoperative pain; maternal satisfaction; Pain management; Ethiopia.Item Isolated Pathogens, Antimicrobial Resistance Patterns and Associated Risk Factors Among Pediatric ICU Patients Beyond the Neonatal Age Group at Asella Teaching and Referral Hospital(2025-05-01) Abdi HayatoABSTRACT Background: Antimicrobial resistance (AMR) is a global public health crisis. Pediatric intensive care units (PICUs) provide care for critically ill children who are at high risk for infections caused by multidrug-resistant (MDR) pathogens. Patients with infections caused by drug-resistant bacteria are at increased risk of worse clinical outcomes including death and increased health care cost. Objectives: To assess the isolated microbial pathogens, antimicrobial resistance patterns, and associated risk factors among PICU patients beyond the neonatal age group at Asella Teaching and Referral Hospital (ATRH). Method: A hospital-based cross-sectional study was conducted using medical records of children aged 29 days to 14 years admitted to the PICU of ATRH. Medical records of 217 patients meeting inclusion criteria were included. Data wase coded and entered in to EPI-INFO version 7.2.7.0 and analyzed by Statistical Package for Social Science (SPSS) version 27. In the binary logistic regression analysis odds ratios (OR), 95 % confidence intervals (CI) and P-values was used to determine factors associated with AMR. Variables with P <0.25 in the bivariate analysis was analyzed for multivariate logistic regression. A P-value of less than 0.05 will be considered statistically significant. Results: Among 217 pediatric ICU admissions, 114 (52.5%) had positive cultures, and 66 isolates underwent antimicrobial susceptibility testing. Coagulase-negative staphylococci were the most frequent isolated organisms, followed by Klebsiella and Enterobacter species. High-risk Antimicrobial resistance (AMR) was identified in 45 (68.2%) isolates. Prolonged PICU stay (>7 days) was independently associated with high-risk AMR (AOR = 7.59; 95% CI: 1.10–52.60). Mortality during PICU admission was also significantly associated with high-risk AMR (AOR = 8.22; 95% CI: 1.39–48.63). Conclusion: A high prevalence of high-risk antimicrobial resistance was observed among pediatric patients admitted to the PICU. The findings are consistent with Ethiopian hospital-based studies and WHO global surveillance reports. Prolonged length of stay in the PICU and death during PICU admission were significantly associated with high-risk antimicrobial resistance. These findings highlight the close relationship between hospitalization duration, disease severity, and high-risk antimicrobial resistance, and emphasize the need for targeted interventions in pediatric intensive care settings. Key words: Antimicrobial resistance, Pediatric ICU, Hospital-acquired infections, Asella, EthiopiaItem PREDICTORS OF PROLONGED HOSPITAL STAY AMONG CHILDREN AGED 3 MONTHS TO 14 YEARS ADMITTED WITH SEVERE PNEUMONIA AT ASELLA REFERRAL AND TEACHING HOSPITAL, SOUTHEAST ETHIOPIA, 2024/2025(2025-05-01) MUBAREK REDWANAbstract Background: Severe pneumonia is a leading cause of hospitalization and death among children under five, especially in low-income countries like Ethiopia.Various factors such as malnutrition, Anemia, Comorbidities, and delayed treatment are associated with prolonged hospital stay in children with severe pneumonia. Prolonged hospital stay increases health care costs, risks of hospital acquired infections, and resource burden on health systems. Objective: This study aimed to determine the magnitude of prolonged hospital stay and identify its predictors among pediatric patients admitted with severe pneumonia at Asella referral and teaching hospital, Arsi zone, southeast, Ethiopia from 2024 to 2025. Methods: A hospital based retrospective cross-sectional study was conducted using secondary data analysis on pediatric patients with severe pneumonia. Data was entered into Microsoft Excel for data cleaning, coding, and preliminary processing, then exported to Statistical Package for Social Sciences (SPSS) version 27.0.1 for analysis. Bivariate logistic regression analysis at a significance level of 0.25 and multivariate logistic regression analyses with a significance level of 0.05 were conducted to determine the factors associated with prolonged hospital stay among pediatric patients. Results: In this study 42% (95% CI: 37.21%- 46.81%) of patients with severe Pneumonia had prolonged hospital stays. The presence of underlying comorbidity (adjusted odds ratio [AOR]: 3.16, 95% CI: [1.832-5.336]), unvaccinated status (AOR: 2.01, 95% CI [1.694-3.815]), Malnutrition (AOR: 2.94,95% CI [1.383-6.290]),having history of previous pneumonia (AOR: 3.277, 95% CI [1.798-5.971]) and delayed in seeking health care provider( AOR: 3.773; CI [2.037-6.989] were independent predictors of prolonged hospital stay among pediatric patients with severe pneumonia. Conclusion: In this study, more than one-third of pediatric patients with severe pneumonia had a length of stay of more than 5 days, and not vaccination status, malnutrition, previous history of pneumonia, delayed health care seeking, and underlying comorbidities were independent predictors of prolonged hospital stay. Therefore, healthcare providers, parents, and other stakeholders should work to improve vaccination rate, improve community early health care seeking behavior through education, and inpatient management of malnutrition and other comorbid diseases to reduce hospital stays for pediatric patients with severe pneumonia. Key words: pediatric patients, prolonged hospital stay, severe pneumonia, southeast EthiopiaItem Magnitude and Associated Factors of Meconium Aspiration Syndrome among Neonates Admitted to Asella Referral and Teaching Hospital, Southeast Ethiopia(2025-05-01) Tsegaye ZebenuAbstract Background: Meconium Aspiration Syndrome (MAS) remains a major cause of neonatal morbidity and mortality, particularly in low- and middle-income countries such as Ethiopia. Despite global efforts to reduce perinatal complications, MAS continues to pose significant clinical challenges, especially in resource-constrained healthcare settings. Understanding its magnitude and associated risk factors is critical for developing effective prevention and management strategies. There is a notable lack of data regarding the burden and contributing factors of MAS among neonates admitted to Asella Referral and Teaching Hospital, a key referral center in Southeast Ethiopia. This study aims to address this knowledge gap by assessing the magnitude and associated factors of MAS in this setting. Objective: To assess the magnitude and associated factors of meconium aspiration syndrome among neonates admitted to Asella Referral and Teaching Hospital, Southeast Ethiopia, from September 2024 to November 2025. Method: A cross-sectional study was conducted among neonates admitted to the Neonatal Intensive Care Unit of Asella Referral and Teaching Hospital. A systematic random sampling technique was employed and a total of 295 neonates were included in the analysis. The diagnosis of meconium aspiration syndrome was made based on clinical criteria. Descriptive statistics were used to determine the magnitude of MAS. Bivariable and multivariable logistic regression analyses were performed to identify factors associated with MAS. Statistical significance was declared at a p-value < 0.05 with a 95% confidence interval. Result: The magnitude of meconium aspiration syndrome among admitted neonates was 19% at 95% CI. Gestational age of ≥37 weeks was significantly associated with MAS (AOR = 2.46; 95% CI: 1.05–5.81; p = 0.039). Exposure to meconium-stained amniotic fluid (MSAF) showed a strong association with MAS (AOR = 33.36; 95% CI: 8.61–129.16; p < 0.001). In addition, the requirement for oxygen therapy immediately after birth was also associated with MAS (AOR = 29.41; 95% CI: 5.02–172.37; p < 0.001). Conclusion: Overall, the magnitude of meconium aspiration syndrome was high among admitted neonates. Exposure to meconium-stained amniotic fluid, requirement for oxygen therapy at birth and gestational age were significantly associated with MAS. Understanding these associations is crucial for improving risk assessment, strengthening preventive strategies and optimizing the management of MAS in neonates. Keywords: Neonates, Meconium Aspiration Syndrome, Asella Referral and Teaching Hospital,EthiopiaItem CLINICAL PATTERN AND EARLY SURGICAL OUTCOMES OF INGUINAL HERNIA REPAIR IN ADULTS ADMITTED TO SURGICAL WARDS AT ASELLA TEACHING AND REFERRAL HOSPITAL, ASELLA, ETHIOPIA(2025-05-01) Bedru MohammedABSTRACT Background: Inguinal hernia is one of the most common general surgical conditions worldwide. In low- and middle-income countries, delayed presentation and limited access to elective surgical care contribute to a higher burden of complicated hernias and poorer postoperative outcomes. In Ethiopia, there is limited evidence regarding the clinical pattern and early surgical outcomes of inguinal hernia repair. Objective: To assess the clinical pattern and early surgical outcomes of inguinal hernia repair among adult patients at Asella Teaching and Referral Hospital, Ethiopia. Methods: An institutional-based cross-sectional study was conducted from July 2022 to July 2025 among adult patients who underwent inguinal hernia repair. Patient charts were retrieved using medical record numbers from operation theater logbooks and surgical ward admission registers. Data were entered into Kobo Toolbox, then coded, cleaned, and exported to the latest version of SPSS for analysis. Bivariate analysis was performed to assess associations between independent variables and postoperative outcomes. Variables with a p-value ≤ 0.25 in the bivariate analysis were entered into a multivariable logistic regression model. Adjusted Odds Ratios (AORs) with 95% Confidence Intervals (CIs) were calculated, and variables with a p-value ≤ 0.05 were considered statistically significant. Results: A total of 114 patient records were analyzed. Most patients were male (73.7%), with a median age of 47 years. The majority of hernias were primary (91.2%), and indirect (75.4). Elective repairs accounted for 88.6% of cases, while 11.4% were emergencies. Tissue repair techniques predominated, with Desarda repair performed in 68.4% of patients. Postoperative complications occurred in 16.7% of cases, with surgical site infection being the most common (4.3%). On multivariable analysis, emergency presentation (AOR = 11.9; p = 0.001) and comorbidities (AOR = 10.6; p < 0.001) were independent predictors of adverse postoperative outcomes. Conclusion: Early postoperative outcomes were generally acceptable. However, emergency presentation and comorbid conditions significantly increased the risk of complications. Optimizing comorbidities and strengthening elective surgical services may improve outcomes in our settings. Keywords: Inguinal hernia; clinical pattern; early surgical outcomes; hernia repair; Ethiopia.
